Born in Minneapolis, Linda Karshan attended Skidmore College, New York. At Skidmore she studied drawing and painting. She subsequently went on to study art history, first at the Sorbonne in Paris and then at the Slade School of Art in London. Continuing her studies, Karshan took a masters degree in psychology which fed into her exploration of the process of drawing.
Karshan's solo museum exhibitions include Folkwang Museum, Essen, Germany, Kettle's Yard, Cambridge, UK, Sir John Soane's Museum, London, UK, and Institut Valencia d'Art Modern, Valencia, Spain. Her works were featured in group exhibitions at the Courtauld Gallery, London, UK, British Museum, London, UK and Graphische Sammlung, Munich, Germany, among others. She regularly exhibits with galleries in Europe, and with ART 3 in Brooklyn, NY.